The Bristol Myers Squibb story
Bristol Myers Squibb makes cancer and blood-thinning drugs, with its transition depending on whether newer medicines can replace Revlimid and eventually Eliquis as patent protection fades.
Written from Bristol Myers Squibb's own filings with the SEC, and rewritten when it publishes a new earnings release. Updated 2026-09-30.
- $63.88share price, last close
- $130.5Bmarket value
- 24/36TenQ Score checks passed
- -0.3%growth a year the price assumes
The story in brief
- Newer medicines lead. In the quarter to June 2026, Growth Portfolio revenue rose 15% to $7.6 billion, while Legacy Portfolio revenue fell 4% to $5.4 billion.
- Higher revenue outlook. Bristol Myers Squibb raised its 2026 revenue guidance to approximately $49.0 billion to $50.0 billion after revenue reached $13.0 billion in the quarter to June 2026.
- Cash supports the transition. Free cash flow over the last twelve months was $11.4 billion, alongside total debt of $43.1 billion and cash and short-term investments of $11.1 billion.
What drives the business
- Bristol Myers Squibb depends on developing and commercializing new medicines to replace revenue lost when established products lose market exclusivity, including Revlimid, Eliquis, Opdivo and Orencia.
- Growth Portfolio revenue increased 15% to $7.6 billion in the quarter to June 2026, driven by Opdivo Qvantig, Reblozyl, Camzyos, Breyanzi and Opdualag.
- Eliquis demand increased in the quarter to June 2026, but generic competition across the rest of the Legacy Portfolio more than offset that strength, leaving portfolio revenue down 4% at $5.4 billion.
- Cobenfy, the schizophrenia medicine acquired with Karuna, generated $63 million in the quarter to June 2026, compared with $27 million in the quarter to March 2025.
- The May 2026 collaboration and licensing agreements with Hengrui Pharma cover 13 early-stage programs in oncology, hematology and immunology, extending the pipeline beyond medicines already on the market.
What the price assumes
At $63.88, the reverse DCF implies that free cash flow after stock pay grows -0.3% a year for ten years, using a 10.2% discount rate.
That compares with delivered annual growth of 19.7% over the last 10 years and the TenQ check's 11.8% bar, which slows that historical record halfway toward 4%.
The free cash flow yield of 8.8% is below its historical comparison of 11.2%, so the cash yield check fails despite the limited growth implied by the reverse DCF.
What could change the story
- Generic lenalidomide licenses in the United States ceased being volume-limited on January 31, 2026, while generic Eliquis competition in some European countries shows that revenue erosion can precede expected patent expiration.
- Clinical setbacks, delayed approvals and tighter drug reimbursement could limit how quickly new medicines replace lost revenue.
- Revenue growth of 3.1% over the last twelve months and annual growth of 1.4% over the last three years both failed TenQ's sector growth checks, despite faster Growth Portfolio expansion.
- Total debt of $43.1 billion exceeds cash and short-term investments of $11.1 billion, and debt relative to equity rose to 1.93 from 1.24 five years earlier, failing both debt checks.
- Alongside collaborations with NVIDIA and Anthropic, Bristol Myers Squibb added a warning that artificial intelligence use and technology sharing with partners may increase competitive, regulatory, litigation and cybersecurity risks.
What to watch next
- The next releases will test the raised 2026 revenue guidance of approximately $49.0 billion to $50.0 billion and non-GAAP EPS guidance of $6.75 to $7.00.
- Eliquis revenue growth against management's 20% to 25% guidance for 2026, compared with 2025, will show how much support the legacy business continues to provide.
- Growth Portfolio revenue, Cobenfy adoption and gross margin will help show whether the product transition is sustaining profitability, after GAAP gross margin fell to 71.3% from 72.5% in the quarter to June 2026.
- Pipeline updates will establish progress toward FDA decision dates of March 11, 2027 for the Reblozyl application and May 13, 2027 for mezigdomide.
Sources
- Bristol Myers Squibb's earnings release, filed with the SEC
- Its latest 10-Q or 10-K, for the risk factors
- The BMY stock report, for every figure and check